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ea0090p406 | Pituitary and Neuroendocrinology | ECE2023

Somatotroph Pituitary Neuroendocrine Tumors (Pitnets)/Adenomas Expressing Steroidogenic Factor (SF1)

Guaraldi Federica , Roncaroli Federico , Villa Chiara , Zoli Matteo , Waqar Mueez , Higham Claire , Lally Imogen , Baussart Bertrand , Assie Guillaume , Morandi Luca , Mazzatenta Diego , Asioli Sofia

Rationale and aim: A recent pangenomic study documented a subset of somatotroph mostly GNAS-wildtype PitNET/adenomas co-express steroidogenic factor 1 (SF1). Aim of our study was to investigate clinical and molecular features of a cohort of these tumour subtype. Study sample: We identified 20 cases of SF1-expressing somatotropinomas out of 173 (11.6%) operated via transsphenoidal endoscopic approach in 3 referral Pituitary Centers patients. Pre- and post...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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